解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::We describe a patient with transient ischemic attacks secondary to a giant aneurysm who showed increased activity on platelet scintigrams at the origin of the left vertebral artery. This is assumed to be the first report of a presumed embolizing aneurysm with positive activity of labeled platelets. Platelet scintigrap...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.5.687
更新日期:1989-05-01 00:00:00
abstract::Platelet activating factor, a potent inducer of in vivo platelet activation and thrombosis, has been shown to be excessively active in acute ischemic stroke patients. Therefore, we studied the effect of aspirin/dipyridamole therapy in inhibiting platelet activating factor-induced platelet activation in acute ischemic ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.5.609
更新日期:1989-05-01 00:00:00
abstract::We produced cerebral vasospasm in 29 dogs by the "two-hemorrhage" method of intracisternal injections, 2 days apart, of autogenous arterial blood. Leukotriene (LT) C4, LTD4, and LTE4 were purified from incubated basilar artery, medulla oblongata, hypothalamus, median eminence, and blood clot from around the basilar ar...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.4.527
更新日期:1989-04-01 00:00:00
abstract::We measured cerebrovascular reactivity to carbon dioxide in the cerebral cortex and the subcortical white matter of 12 healthy adult volunteers (four young subjects aged 21-24, four middle-aged subjects aged 34-40, and four elderly subjects aged 62-85 years). Blood flow was computed from the concentration history of x...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.20.4.453
更新日期:1989-04-01 00:00:00
abstract::In a randomized pilot study we compared the efficacy of temporary anticoagulation with intravenous heparin sodium to the efficacy of aspirin in preventing cerebral infarction in hospitalized patients with recent (less than 7 days) transient ischemic attacks (TIAs). Fifty-five patients (33 men, 22 women) aged 36-81 (me...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.str.20.4.441
更新日期:1989-04-01 00:00:00
abstract::We used 44 splenectomized dogs to study the effects of isovolemic hemodilution with a crystalloid solution. The dogs were randomly divided into a hemodilution and a control group. In each group, 17 dogs were subjected to 6 hours of internal carotid and middle cerebral artery occlusion, and five dogs received sham oper...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.4.534
更新日期:1989-04-01 00:00:00
abstract::A 25-year-old black man with sarcoidosis presented with transient ischemic attacks followed by sudden, persistent right hemiparesis. He gave a history of recent, recurrent lower motor neuron facial palsy. Computed tomography demonstrated an infarct in the left internal capsule. Chest x-ray film showed bilateral hilar ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.3.400
更新日期:1989-03-01 00:00:00
abstract::To determine the incidence of perioperative silent cerebral infarction, 97 patients who underwent carotid endarterectomy were prospectively studied with preoperative and postoperative computed tomograms. Thirty-one of 96 patients (32%) had findings of cerebral infarction on preoperative computed tomograms. Silent cere...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.3.329
更新日期:1989-03-01 00:00:00
abstract::We observed the effects of a new thyrotropin-releasing hormone derivative, YM-14673 (N alpha-[[(S)-4-oxo-2-azetidinyl]carbonyl]-L-histidyl-L-prolinamide dihydrate), on behavioral changes in rats for 3 weeks after focal cerebral ischemia. Under halothane anesthesia, the left middle cerebral artery was occluded via a tr...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.3.362
更新日期:1989-03-01 00:00:00
abstract::I provide the theoretical basis for an error calculus for measurements of cerebral blood flow using a freely diffusible tracer substance such as xenon-133. The use of the error calculus is exemplified by a study of the effect on the error margins in measurements of gray matter blood flow from flow level, relative weig...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.2.205
更新日期:1989-02-01 00:00:00
abstract::Choline concentration is rate limiting in the synthesis of acetylcholine. There is a negative arteriovenous difference for choline concentration across the brain, indicating the steady output of choline from this organ. Cerebral ischemia may increase extracellular choline concentration by interfering with its removal ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.1.92
更新日期:1989-01-01 00:00:00
abstract::We reviewed demographic data on patients having 2,256 carotid endarterectomies in eight large hospitals in North Carolina to determine the frequency of blacks among these patients. Blacks comprised only 4.6% of the patients having carotid endarterectomy even though they comprised 26% of all patients discharged and 22%...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.1.22
更新日期:1989-01-01 00:00:00
abstract::We devised the present experiments to assess the effects of ischemia on the production of dopamine in the caudate nucleus of spontaneously hypertensive stroke-resistant rats. Ringer's solution was continuously perfused at a rate of 10 microliters/min through 0.2-mm-diameter dialysis tubing implanted in the rat's cauda...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.12.1540
更新日期:1988-12-01 00:00:00
abstract::We mapped average age-adjusted stroke mortality rates for white men and white women aged 35-74 years for state economic areas (counties or groups of counties) in the continental United States for three 7-year periods between 1962 and 1982. Despite the decline of national stroke mortality rates, rates in some areas fai...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.12.1507
更新日期:1988-12-01 00:00:00
abstract::Before surgery, we evaluated major intracranial collateral pathways using transcranial Doppler ultrasonography (TCD) in 50 patients who then underwent carotid endarterectomy with concurrent multimodality cerebral monitoring. Patients were grouped with respect to collateral pathways demonstrated preoperatively by TCD: ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.11.1328
更新日期:1988-11-01 00:00:00
abstract::Life table analysis is a powerful statistical tool that has become the preferred technique for studying both the natural history of and the effect of treatment on disease outcome. We have found only one report using life table analysis to study rehabilitation outcome after stroke. We assessed the recovery of both inde...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.11.1354
更新日期:1988-11-01 00:00:00
abstract::Hyperventilation to extremely low arterial carbon dioxide tension (PaCO2) has been used in the management of persistent pulmonary hypertension in newborn infants. With progressive hypocarbia, cerebral vasoconstriction occurs, raising the concern that extreme hypocarbia may result in cerebral oxygen deprivation. Theref...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.11.1365
更新日期:1988-11-01 00:00:00
abstract::The effect of very-low-dose aspirin as an antithrombotic agent was evaluated blindly in 301 patients who had recently undergone carotid endarterectomy. After randomization, 150 patients received aspirin and 151 received placebo. The two groups were comparable with regard to age, sex, blood pressure, previous cerebrova...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.str.19.10.1211
更新日期:1988-10-01 00:00:00
abstract::In this retrospective analysis we report our treatment experience in 65 consecutive patients with clinical signs of severe brainstem ischemia with angiographically demonstrated thrombotic vertebrobasilar artery occlusions who received either local intra-arterial thrombolytic therapy (urokinase or streptokinase) (43 pa...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.10.1216
更新日期:1988-10-01 00:00:00
abstract::We studied the effects of the calcium channel blocker nicardipine on regional tissue Ca2+, Na+, K+, and water shifts in the brains of seven Sprague-Dawley rats after permanent occlusions of the middle cerebral artery. We also assessed the entry of [14C]nicardipine into the brains of five rats; the highest concentratio...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.9.1125
更新日期:1988-09-01 00:00:00
abstract::Sixteen acceptably randomized studies of anticoagulant therapy after cerebral or retinal ischemia or infarction are reviewed and the results among 1,046 anticoagulated patients and 1,071 controls are analyzed. The following conclusions are derived. 1) Anticoagulant therapy has not been shown to be better than control ...
journal_title:Stroke
pub_type: 临床试验,杂志文章,评审
doi:10.1161/01.str.19.8.1043
更新日期:1988-08-01 00:00:00
abstract::Acute cerebral circulatory changes following experimental cerebral hemorrhage were investigated in eight cats. The cerebral hemorrhage was produced in the right basal ganglia by introducing arterial blood via a thin catheter, using the systemic arterial blood pressure of the cat as a driving force. Local cerebral bloo...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.8.991
更新日期:1988-08-01 00:00:00
abstract::To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.8.1020
更新日期:1988-08-01 00:00:00
abstract::We evaluated the effects of aging and hypertension on endothelium-dependent relaxation of rat common carotid arteries using 14-week-old (young) and 11-month-old (old) Wistar-Kyoto rats (WKY) and age-matched spontaneously hypertensive rats (SHR). Isometric tension of common carotid artery ring segments was measured. Wi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.7.892
更新日期:1988-07-01 00:00:00
abstract::TCD recording of flow velocities in intracranial vessels was first described by Aaslid in 1982. The utility of this instrument becomes more apparent as it is used in different clinical settings and compared with angiographic findings (Figures 1 and 2). Its importance in early detection of vasospasm in subarachnoid hem...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.7.915
更新日期:1988-07-01 00:00:00
abstract::The reactivity of cerebral blood vessels to changes in PaCO2 in areas of the cerebral cortex with or without diaschisis was investigated in 13 patients in a subacute or chronic stage after a small capsular infarct. A focal area of hypoperfusion (area of diaschisis) was detected in the ipsilateral sensorimotor cortex i...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.7.840
更新日期:1988-07-01 00:00:00
abstract::Transient visual disturbance following cardiac catheterization has been regarded as a benign and transient complication. We describe two cases of computed-tomography-documented occipital infarction after cardiac catheterization that emphasize a complication more serious than previously thought. ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.6.773
更新日期:1988-06-01 00:00:00
abstract::Neurogenically caused cardiac arrhythmias and their correlation to lesions within the central nervous system were examined prospectively in 54 patients with spontaneous intracerebral hemorrhage. All patients were examined neurologically daily for 3 weeks, with special attention given to signs of brainstem compression ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.6.688
更新日期:1988-06-01 00:00:00
abstract::Blood flow velocity of the middle cerebral artery was monitored during cardiopulmonary bypass procedures by means of transcranial Doppler ultrasonography. Our investigation was carried out in a group of 16 patients with severe carotid stenosis or occlusion and in a control group of 42 patients with no or stenosis of l...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.6.674
更新日期:1988-06-01 00:00:00
abstract::Atrial septal aneurysm is an uncommon occult cardiac source of cerebral embolism. It is usually asymptomatic, and clinical cardiologic examination and electrocardiography fail to reveal its presence. We report a case of a 34-year-old woman with sudden right hemiplegia and aphasia from occlusion of the left carotid sip...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.5.640
更新日期:1988-05-01 00:00:00
abstract::The plasma concentrations of protein C, an anticoagulant protein, and fibrinopeptide A were measured in 37 patients with acute hemispheric stroke and in age-matched controls with nonvascular neurologic diseases. In 11 stroke patients who died within 15 days after the onset (nonsurvivors) protein C antigen concentratio...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.5.579
更新日期:1988-05-01 00:00:00
abstract::Neurologic deficits that occur simultaneously with or subsequent to internal carotid artery occlusion may be influenced by the adequacy of the intracerebral collateral circulation. Transcranial Doppler ultrasonography was used to evaluate mean middle cerebral artery blood velocity and blood flow in major collateral ar...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.5.589
更新日期:1988-05-01 00:00:00
abstract::To elucidate the role of the internal elastic lamina in the development of cerebral aneurysm, the bifurcation of the anterior cerebral artery and olfactory artery was histologically studied in control and experimental rats treated with unilateral carotid ligation and renal hypertension. Various stages of aneurysm form...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.4.507
更新日期:1988-04-01 00:00:00
abstract::The morphologic description and measurements of endarterectomy specimens are usually believed to be accurate and are used as the gold standard against which the findings of diagnostic procedures are judged. Pathology data on 289 endarterectomy specimens from five participating centers and the corresponding angiography...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.3.289
更新日期:1988-03-01 00:00:00
abstract::Using transesophageal echocardiography, cardiac structures can be imaged with high resolution. The aim of our study was to evaluate whether transesophageal echocardiography is superior in detecting mitral valve prolapse and other cardiac abnormalities compared with transthoracic echocardiography in an age-matched cont...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.3.345
更新日期:1988-03-01 00:00:00
abstract::In a postasphyxia neonatal lamb model, the responses of the cerebral circulation to hypoxic hypoxia and changes in systemic arterial blood pressure were examined. Ventilated newborn lambs (n = 14) were subjected to a gradual asphyxial insult, resuscitated, and returned to control ventilator settings. During the time 2...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.2.239
更新日期:1988-02-01 00:00:00
abstract::During the 5-year period from 1980 to 1984, the incidence of subarachnoid hemorrhage due only to rupture of aneurysms was investigated in Izumo City, a small city with a population of 79,026. Additionally, to ascertain the relation of incidence to the size of the geographic area and/or population, a similar analysis w...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.2.170
更新日期:1988-02-01 00:00:00
abstract::The nature of alpha-adrenergic receptors in human cerebral arteries was characterized, and alteration of these receptors after subarachnoid hemorrhage was examined using a radioligand binding assay. Norepinephrine content of control arteries was also analyzed and compared with that of arteries after subarachnoid hemor...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.1.80
更新日期:1988-01-01 00:00:00
abstract::The frequency of clinically significant coronary artery disease (CAD) among stroke patients and the impact of CAD on stroke rehabilitation were studied in 132 patients with first thrombotic or embolic stroke who participated in comprehensive rehabilitation. Sixty-one patients (46%) had a history of CAD, and 16 of the ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.1.42
更新日期:1988-01-01 00:00:00
abstract::Forty-five patients with symptomatic (20 with transient ischemic attack, 25 with minor stroke) greater than or equal to 75% stenosis of the cervical internal carotid artery had no endarterectomy and received only medical therapy because the surgical risks (severe cardiac disease, chronic obstructive pulmonary disease,...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.1.108
更新日期:1988-01-01 00:00:00